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1m7i

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[[Image:1m7i.png|left|200px]]
 
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{{STRUCTURE_1m7i| PDB=1m7i | SCENE= }}
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==CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE==
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<StructureSection load='1m7i' size='340' side='right'caption='[[1m7i]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1m7i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M7I FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12427018}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RAM:ALPHA-L-RHAMNOSE'>RAM</scene>, <scene name='pdbligand=RAO:1-O-METHYL-ALPHA-RHAMNOSE'>RAO</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7i OCA], [https://pdbe.org/1m7i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m7i RCSB], [https://www.ebi.ac.uk/pdbsum/1m7i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m7i ProSAT]</span></td></tr>
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[[1m7i]] is a 2 chain structure of [[Monoclonal Antibody]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M7I OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A2NHM3_MOUSE A2NHM3_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m7/1m7i_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1m7i ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Monoclonal Antibody|Monoclonal Antibody]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:012427018</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Bundle, D R.]]
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[[Category: Bundle DR]]
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[[Category: Chervenak, M C.]]
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[[Category: Chervenak MC]]
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[[Category: Johnson, M A.]]
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[[Category: Johnson MA]]
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[[Category: Pinto, B M.]]
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[[Category: Pinto BM]]
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[[Category: Quiocho, F A.]]
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[[Category: Quiocho FA]]
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[[Category: Vyas, M N.]]
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[[Category: Vyas MN]]
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[[Category: Vyas, N K.]]
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[[Category: Vyas NK]]
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[[Category: And anti-carbohydrate antibody]]
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[[Category: Fab-carbohydrate interaction]]
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[[Category: Immune system]]
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[[Category: Shigella o-antigen]]
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Current revision

CRYSTAL STRUCTURE OF A MONOCLONAL FAB SPECIFIC FOR SHIGELLA FLEXNERI Y LIPOPOLYSACCHARIDE COMPLEXED WITH A PENTASACCHARIDE

PDB ID 1m7i

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