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1mdo
From Proteopedia
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| - | [[Image:1mdo.png|left|200px]] | ||
| - | + | ==Crystal structure of ArnB aminotransferase with pyridomine 5' phosphate== | |
| + | <StructureSection load='1mdo' size='340' side='right'caption='[[1mdo]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1mdo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MDO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mdo OCA], [https://pdbe.org/1mdo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mdo RCSB], [https://www.ebi.ac.uk/pdbsum/1mdo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mdo ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ARNB_SALTY ARNB_SALTY] Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity).[HAMAP-Rule:MF_01167] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/1mdo_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mdo ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Aminotransferase 3D structures|Aminotransferase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[ | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| - | + | [[Category: Badger J]] | |
| - | + | [[Category: Buchanan MD]] | |
| - | + | [[Category: Buchanan SG]] | |
| - | [[Category: Salmonella enterica subsp. enterica serovar | + | [[Category: Christopher JA]] |
| - | [[Category: Badger | + | [[Category: Gajiwala K]] |
| - | [[Category: Buchanan | + | [[Category: Hendle J]] |
| - | [[Category: Buchanan | + | [[Category: Muller-Dieckmann H-J]] |
| - | [[Category: Christopher | + | [[Category: Newman JM]] |
| - | [[Category: Gajiwala | + | [[Category: Noland BW]] |
| - | [[Category: Hendle | + | [[Category: Rutter ME]] |
| - | [[Category: Muller-Dieckmann | + | [[Category: Sanderson WE]] |
| - | [[Category: Newman | + | [[Category: Sauder JM]] |
| - | [[Category: Noland | + | [[Category: Tresser J]] |
| - | [[Category: Rutter | + | [[Category: Wright T]] |
| - | [[Category: Sanderson | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | + | ||
Current revision
Crystal structure of ArnB aminotransferase with pyridomine 5' phosphate
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