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1mfw

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[[Image:1mfw.png|left|200px]]
 
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{{STRUCTURE_1mfw| PDB=1mfw | SCENE= }}
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==STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: SELENOMETHIONINE LABELED PROTEIN==
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<StructureSection load='1mfw' size='340' side='right'caption='[[1mfw]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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===STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: SELENOMETHIONINE LABELED PROTEIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1mfw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MFW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MFW FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12692530}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mfw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mfw OCA], [https://pdbe.org/1mfw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mfw RCSB], [https://www.ebi.ac.uk/pdbsum/1mfw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mfw ProSAT]</span></td></tr>
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[[1mfw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MFW OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/DCLK1_HUMAN DCLK1_HUMAN] Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.
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<ref group="xtra">PMID:012692530</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mf/1mfw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mfw ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bushweller, J H.]]
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[[Category: Large Structures]]
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[[Category: Cierpickil, T.]]
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[[Category: Bushweller JH]]
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[[Category: Dauter, Z.]]
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[[Category: Cierpickil T]]
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[[Category: Derewenda, U.]]
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[[Category: Dauter Z]]
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[[Category: Derewenda, Z.]]
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[[Category: Derewenda U]]
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[[Category: Devedjiev, Y.]]
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[[Category: Derewenda Z]]
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[[Category: Feng, Y.]]
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[[Category: Devedjiev Y]]
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[[Category: Kim, M H.]]
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[[Category: Feng Y]]
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[[Category: Krowarsch, D.]]
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[[Category: Kim MH]]
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[[Category: Otlewski, J.]]
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[[Category: Krowarsch D]]
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[[Category: Walsh, C A.]]
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[[Category: Otlewski J]]
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[[Category: Cortex development]]
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[[Category: Walsh CA]]
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[[Category: Doublecortin]]
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[[Category: Doublecortin-like kinase]]
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[[Category: Microtubule bundling]]
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[[Category: Transferase]]
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Current revision

STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: SELENOMETHIONINE LABELED PROTEIN

PDB ID 1mfw

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