This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1mh5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:36, 10 April 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_1mh5| PDB=1mh5 | SCENE= }}
 
-
===The Structure Of The Complex Of The Fab Fragment Of The Esterolytic Antibody MS6-164 and A Transition-State Analog===
 
-
{{ABSTRACT_PUBMED_12948492}}
 
-
==About this Structure==
+
==The Structure Of The Complex Of The Fab Fragment Of The Esterolytic Antibody MS6-164 and A Transition-State Analog==
-
[[1mh5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH5 OCA].
+
<StructureSection load='1mh5' size='340' side='right'caption='[[1mh5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1mh5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MH5 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HAL:N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE'>HAL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mh5 OCA], [https://pdbe.org/1mh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mh5 RCSB], [https://www.ebi.ac.uk/pdbsum/1mh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mh5 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/IGKC_MOUSE IGKC_MOUSE]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/1mh5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mh5 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Monoclonal Antibody|Monoclonal Antibody]]
+
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:012948492</ref><references group="xtra"/><references/>
+
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Blackburn, G M.]]
+
[[Category: Blackburn GM]]
-
[[Category: Kakinuma, H.]]
+
[[Category: Kakinuma H]]
-
[[Category: Muranova, T A.]]
+
[[Category: Muranova TA]]
-
[[Category: Murray, I A.]]
+
[[Category: Murray IA]]
-
[[Category: Nishi, Y.]]
+
[[Category: Nishi Y]]
-
[[Category: Partridge, L J.]]
+
[[Category: Partridge LJ]]
-
[[Category: Rice, D W.]]
+
[[Category: Rice DW]]
-
[[Category: Ruzheinikov, S N.]]
+
[[Category: Ruzheinikov SN]]
-
[[Category: Sedelnikova, S E.]]
+
[[Category: Sedelnikova SE]]
-
[[Category: Shimazaki, K.]]
+
[[Category: Shimazaki K]]
-
[[Category: Sun, J.]]
+
[[Category: Sun J]]
-
[[Category: Takashi, N.]]
+
[[Category: Takashi N]]
-
[[Category: Catalytic antibody]]
+
-
[[Category: Ester hydrolysis]]
+
-
[[Category: Esterolytic]]
+
-
[[Category: Fab]]
+
-
[[Category: Immune system]]
+
-
[[Category: Immunoglobulin]]
+

Current revision

The Structure Of The Complex Of The Fab Fragment Of The Esterolytic Antibody MS6-164 and A Transition-State Analog

PDB ID 1mh5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools