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1mk0

From Proteopedia

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{{Seed}}
 
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[[Image:1mk0.png|left|200px]]
 
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==catalytic domain of intron endonuclease I-TevI, E75A mutant==
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The line below this paragraph, containing "STRUCTURE_1mk0", creates the "Structure Box" on the page.
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<StructureSection load='1mk0' size='340' side='right'caption='[[1mk0]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mk0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MK0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
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{{STRUCTURE_1mk0| PDB=1mk0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mk0 OCA], [https://pdbe.org/1mk0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mk0 RCSB], [https://www.ebi.ac.uk/pdbsum/1mk0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mk0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TEV1_BPT4 TEV1_BPT4] This endonuclease is specific to the thymidylate synthase (td) gene splice junction and is involved in intron homing.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/1mk0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mk0 ConSurf].
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<div style="clear:both"></div>
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===catalytic domain of intron endonuclease I-TevI, E75A mutant===
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==See Also==
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12379841}}, adds the Publication Abstract to the page
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[[Category: Escherichia virus T4]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12379841 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Belfort M]]
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{{ABSTRACT_PUBMED_12379841}}
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[[Category: Derbyshire V]]
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[[Category: Kowalski JC]]
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==About this Structure==
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[[Category: Meehan L]]
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1MK0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MK0 OCA].
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[[Category: Van Roey P]]
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==Reference==
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Catalytic domain structure and hypothesis for function of GIY-YIG intron endonuclease I-TevI., Van Roey P, Meehan L, Kowalski JC, Belfort M, Derbyshire V, Nat Struct Biol. 2002 Nov;9(11):806-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12379841 12379841]
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[[Category: Enterobacteria phage t4]]
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[[Category: Single protein]]
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[[Category: Belfort, M.]]
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[[Category: Derbyshire, V.]]
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[[Category: Kowalski, J C.]]
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[[Category: Meehan, L.]]
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[[Category: Roey, P Van.]]
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[[Category: Alpha/beta fold]]
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[[Category: Catalytic domain]]
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[[Category: Dna-binding surface]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 00:09:00 2008''
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Current revision

catalytic domain of intron endonuclease I-TevI, E75A mutant

PDB ID 1mk0

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