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1ml7

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{{Seed}}
 
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[[Image:1ml7.png|left|200px]]
 
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<!--
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==Crystal structure of nitrophorin 4 complexed with 4-iodopyrazole==
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The line below this paragraph, containing "STRUCTURE_1ml7", creates the "Structure Box" on the page.
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<StructureSection load='1ml7' size='340' side='right'caption='[[1ml7]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ml7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ML7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ML7 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEV:5,8-DIMETHYL-1,2,3,4-TETRAVINYLPORPHINE-6,7-DIPROPIONIC+ACID+FERROUS+COMPLEX'>HEV</scene>, <scene name='pdbligand=PYZ:4-IODOPYRAZOLE'>PYZ</scene></td></tr>
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{{STRUCTURE_1ml7| PDB=1ml7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ml7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ml7 OCA], [https://pdbe.org/1ml7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ml7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ml7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ml7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NP4_RHOPR NP4_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ml/1ml7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ml7 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of nitrophorin 4 complexed with 4-iodopyrazole===
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==See Also==
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*[[Nitrophorin|Nitrophorin]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_14673714}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 14673714 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14673714}}
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==About this Structure==
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1ML7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rhodnius_prolixus Rhodnius prolixus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ML7 OCA].
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==Reference==
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<ref group="xtra">PMID:14673714</ref><references group="xtra"/>
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[[Category: Rhodnius prolixus]]
[[Category: Rhodnius prolixus]]
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[[Category: Berry, R E.]]
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[[Category: Berry RE]]
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[[Category: Ding, X D.]]
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[[Category: Ding XD]]
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[[Category: Montfort, W R.]]
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[[Category: Montfort WR]]
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[[Category: Walker, F A.]]
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[[Category: Walker FA]]
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[[Category: Weichsel, A.]]
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[[Category: Weichsel A]]
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[[Category: Beta barrel]]
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[[Category: Conformational change]]
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[[Category: Ferric heme]]
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[[Category: Iodopyrazole]]
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[[Category: Lipocalin]]
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[[Category: No carrier]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:52:09 2009''
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Current revision

Crystal structure of nitrophorin 4 complexed with 4-iodopyrazole

PDB ID 1ml7

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