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1mtz

From Proteopedia

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{{Seed}}
 
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[[Image:1mtz.png|left|200px]]
 
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==Crystal Structure of the Tricorn Interacting Factor F1==
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The line below this paragraph, containing "STRUCTURE_1mtz", creates the "Structure Box" on the page.
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<StructureSection load='1mtz' size='340' side='right'caption='[[1mtz]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1mtz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MTZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mtz OCA], [https://pdbe.org/1mtz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mtz RCSB], [https://www.ebi.ac.uk/pdbsum/1mtz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mtz ProSAT]</span></td></tr>
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{{STRUCTURE_1mtz| PDB=1mtz | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of the Tricorn Interacting Factor F1===
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[https://www.uniprot.org/uniprot/PIP_THEAC PIP_THEAC] Cleaves H-Pro-AMC as well as a wide spectrum of amino acid substrates and several peptide substrates without a proline at the N-terminus. Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome) yielding free amino acids.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_12374735}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 12374735 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mt/1mtz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_12374735}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mtz ConSurf].
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1MTZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MTZ OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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Structures of the tricorn-interacting aminopeptidase F1 with different ligands explain its catalytic mechanism., Goettig P, Groll M, Kim JS, Huber R, Brandstetter H, EMBO J. 2002 Oct 15;21(20):5343-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12374735 12374735]
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[[Category: Large Structures]]
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[[Category: Prolyl aminopeptidase]]
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[[Category: Single protein]]
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[[Category: Thermoplasma acidophilum]]
[[Category: Thermoplasma acidophilum]]
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[[Category: Brandstetter, H.]]
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[[Category: Brandstetter H]]
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[[Category: Goettig, P.]]
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[[Category: Goettig P]]
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[[Category: Groll, M.]]
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[[Category: Groll M]]
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[[Category: Huber, R.]]
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[[Category: Huber R]]
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[[Category: Kim, J S.]]
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[[Category: Kim J-S]]
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[[Category: Alpha-beta hydrolase]]
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[[Category: Caged active site]]
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[[Category: Cap domain]]
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[[Category: Prolyl peptidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:57:36 2008''
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Current revision

Crystal Structure of the Tricorn Interacting Factor F1

PDB ID 1mtz

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