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1n2x

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[[Image:1n2x.png|left|200px]]
 
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==Crystal Structure Analysis of TM0872, a Putative SAM-dependent Methyltransferase, Complexed with SAM==
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The line below this paragraph, containing "STRUCTURE_1n2x", creates the "Structure Box" on the page.
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<StructureSection load='1n2x' size='340' side='right'caption='[[1n2x]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n2x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N2X FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1n2x| PDB=1n2x | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n2x OCA], [https://pdbe.org/1n2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n2x RCSB], [https://www.ebi.ac.uk/pdbsum/1n2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n2x ProSAT], [https://www.topsan.org/Proteins/MCSG/1n2x TOPSAN]</span></td></tr>
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</table>
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===Crystal Structure Analysis of TM0872, a Putative SAM-dependent Methyltransferase, Complexed with SAM===
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== Function ==
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[https://www.uniprot.org/uniprot/RSMH_THEMA RSMH_THEMA] Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.[HAMAP-Rule:MF_01007]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12824489}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12824489 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/1n2x_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12824489}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1n2x]] is a 2 chain structure of [[S-adenosyl-L-methionine-dependent methyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N2X OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n2x ConSurf].
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<div style="clear:both"></div>
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==See Also==
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__TOC__
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*[[S-adenosyl-L-methionine-dependent methyltransferase|S-adenosyl-L-methionine-dependent methyltransferase]]
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</StructureSection>
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[[Category: Large Structures]]
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==Reference==
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<ref group="xtra">PMID:012824489</ref><references group="xtra"/>
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson WF]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Miller DJ]]
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[[Category: Miller, D J.]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Protein-sam methyl donor complex]]
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[[Category: Psi]]
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[[Category: Sam-dependent methyltransferase fold]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal Structure Analysis of TM0872, a Putative SAM-dependent Methyltransferase, Complexed with SAM

PDB ID 1n2x

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