This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1n5a

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:46, 10 April 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1n5a.png|left|200px]]
 
-
<!--
+
==Crystal structure of the Murine class I Major Histocompatibility Complex of H-2DB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV==
-
The line below this paragraph, containing "STRUCTURE_1n5a", creates the "Structure Box" on the page.
+
<StructureSection load='1n5a' size='340' side='right'caption='[[1n5a]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1n5a]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymphocytic_choriomeningitis_mammarenavirus Lymphocytic choriomeningitis mammarenavirus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N5A FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n5a OCA], [https://pdbe.org/1n5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n5a RCSB], [https://www.ebi.ac.uk/pdbsum/1n5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n5a ProSAT]</span></td></tr>
-
{{STRUCTURE_1n5a| PDB=1n5a | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n5/1n5a_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n5a ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of the Murine class I Major Histocompatibility Complex of H-2DB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV===
+
==See Also==
-
 
+
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
-
 
+
*[[MHC 3D structures|MHC 3D structures]]
-
<!--
+
*[[MHC I 3D structures|MHC I 3D structures]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_12479822}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 12479822 is the PubMed ID number.
+
</StructureSection>
-
-->
+
[[Category: Large Structures]]
-
{{ABSTRACT_PUBMED_12479822}}
+
[[Category: Lymphocytic choriomeningitis mammarenavirus]]
-
 
+
-
==About this Structure==
+
-
1N5A is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5A OCA].
+
-
 
+
-
==Reference==
+
-
A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses., Achour A, Michaelsson J, Harris RA, Odeberg J, Grufman P, Sandberg JK, Levitsky V, Karre K, Sandalova T, Schneider G, Immunity. 2002 Dec;17(6):757-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12479822 12479822]
+
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Protein complex]]
+
[[Category: Achour A]]
-
[[Category: Achour, A.]]
+
[[Category: Grufman P]]
-
[[Category: Grufman, P.]]
+
[[Category: Harris RA]]
-
[[Category: Harris, R A.]]
+
[[Category: Karre K]]
-
[[Category: Karre, K.]]
+
[[Category: Levitsky V]]
-
[[Category: Levitsky, V.]]
+
[[Category: Michaelsson J]]
-
[[Category: Michaelsson, J.]]
+
[[Category: Odeberg J]]
-
[[Category: Odeberg, J.]]
+
[[Category: Sandalova T]]
-
[[Category: Sandalova, T.]]
+
[[Category: Sandberg JK]]
-
[[Category: Sandberg, J K.]]
+
[[Category: Schneider G]]
-
[[Category: Schneider, G.]]
+
-
[[Category: Immunodominant epitope]]
+
-
[[Category: Lcmv]]
+
-
[[Category: Murine mhc]]
+
-
[[Category: Viral escape]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:35:42 2008''
+

Current revision

Crystal structure of the Murine class I Major Histocompatibility Complex of H-2DB, B2-Microglobulin, and A 9-Residue immunodominant peptide epitope gp33 derived from LCMV

PDB ID 1n5a

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1n5a"
Personal tools