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1ncb

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[[Image:1ncb.png|left|200px]]
 
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{{STRUCTURE_1ncb| PDB=1ncb | SCENE= }}
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==CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE==
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<StructureSection load='1ncb' size='340' side='right'caption='[[1ncb]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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===CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ncb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/tern/Australia/G70C/1975(H11N9)) Influenza A virus (A/tern/Australia/G70C/1975(H11N9))] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NCB FirstGlance]. <br>
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{{ABSTRACT_PUBMED_1522584}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ncb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ncb OCA], [https://pdbe.org/1ncb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ncb RCSB], [https://www.ebi.ac.uk/pdbsum/1ncb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ncb ProSAT]</span></td></tr>
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[[1ncb]] is a 3 chain structure of [[Antibody]] and [[Neuraminidase]] with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCB OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GCAM_MOUSE GCAM_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/1ncb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ncb ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[Neuraminidase|Neuraminidase]]
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:001522584</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Exo-alpha-sialidase]]
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[[Category: Large Structures]]
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[[Category: Influenza a virus]]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Colman, P M.]]
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[[Category: Colman PM]]
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[[Category: Tulip, W R.]]
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[[Category: Tulip WR]]
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[[Category: Varghese, J N.]]
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[[Category: Varghese JN]]

Current revision

CRYSTAL STRUCTURES OF TWO MUTANT NEURAMINIDASE-ANTIBODY COMPLEXES WITH AMINO ACID SUBSTITUTIONS IN THE INTERFACE

PDB ID 1ncb

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