1ncv

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{{Seed}}
 
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[[Image:1ncv.png|left|200px]]
 
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==DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES==
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The line below this paragraph, containing "STRUCTURE_1ncv", creates the "Structure Box" on the page.
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<StructureSection load='1ncv' size='340' side='right'caption='[[1ncv]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ncv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NCV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ncv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ncv OCA], [https://pdbe.org/1ncv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ncv RCSB], [https://www.ebi.ac.uk/pdbsum/1ncv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ncv ProSAT]</span></td></tr>
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{{STRUCTURE_1ncv| PDB=1ncv | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CCL7_HUMAN CCL7_HUMAN] Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nc/1ncv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ncv ConSurf].
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<div style="clear:both"></div>
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===DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES===
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==See Also==
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*[[Monocyte chemoattractant protein|Monocyte chemoattractant protein]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9109648}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9109648 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9109648}}
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==About this Structure==
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1NCV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NCV OCA].
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==Reference==
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Determination of the three-dimensional structure of CC chemokine monocyte chemoattractant protein 3 by 1H two-dimensional NMR spectroscopy., Meunier S, Bernassau JM, Guillemot JC, Ferrara P, Darbon H, Biochemistry. 1997 Apr 15;36(15):4412-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9109648 9109648]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bernassau, J M.]]
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[[Category: Bernassau JM]]
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[[Category: Darbon, H.]]
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[[Category: Darbon H]]
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[[Category: Ferrara, P.]]
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[[Category: Ferrara P]]
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[[Category: Guillemot, J C.]]
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[[Category: Guillemot JC]]
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[[Category: Meunier, S.]]
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[[Category: Meunier S]]
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[[Category: Beta-chemokine]]
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[[Category: Chemotaxis]]
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[[Category: Cytokine]]
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[[Category: Glycoprotein]]
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[[Category: Heparin-binding]]
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[[Category: Mcp-3]]
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[[Category: Nmr]]
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[[Category: Structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:29:00 2008''
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Current revision

DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES

PDB ID 1ncv

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