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1nez
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1nez" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nez, resolution 2.1Å" /> '''The Crystal Structure...) |
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| - | [[Image:1nez.jpg|left|200px]]<br /><applet load="1nez" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1nez, resolution 2.1Å" /> | ||
| - | '''The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity'''<br /> | ||
| - | == | + | ==The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity== |
| - | TL | + | <StructureSection load='1nez' size='340' side='right'caption='[[1nez]], [[Resolution|resolution]] 2.10Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1nez]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NEZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nez OCA], [https://pdbe.org/1nez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nez RCSB], [https://www.ebi.ac.uk/pdbsum/1nez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nez ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HA1T_MOUSE HA1T_MOUSE] Involved in the presentation of foreign antigens to the immune system. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ne/1nez_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nez ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]] | |
| - | + | *[[CD8 3D structures|CD8 3D structures]] | |
| - | + | *[[MHC 3D structures|MHC 3D structures]] | |
| - | + | *[[MHC I 3D structures|MHC I 3D structures]] | |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Cheroutre | + | </StructureSection> |
| - | [[Category: Joachimiak | + | [[Category: Large Structures]] |
| - | [[Category: Kronenberg | + | [[Category: Mus musculus]] |
| - | [[Category: Liu | + | [[Category: Cheroutre H]] |
| - | [[Category: Liu | + | [[Category: Joachimiak A]] |
| - | [[Category: Naidenko | + | [[Category: Kronenberg M]] |
| - | [[Category: Reinherz | + | [[Category: Liu JH]] |
| - | [[Category: Wang | + | [[Category: Liu Y]] |
| - | [[Category: Xiong | + | [[Category: Naidenko OV]] |
| - | [[Category: Zhang | + | [[Category: Reinherz EL]] |
| - | + | [[Category: Wang JH]] | |
| - | + | [[Category: Xiong Y]] | |
| - | + | [[Category: Zhang R]] | |
| - | + | ||
Current revision
The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity
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Categories: Large Structures | Mus musculus | Cheroutre H | Joachimiak A | Kronenberg M | Liu JH | Liu Y | Naidenko OV | Reinherz EL | Wang JH | Xiong Y | Zhang R
