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1nfr

From Proteopedia

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{{Seed}}
 
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[[Image:1nfr.png|left|200px]]
 
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<!--
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==Rv2002 gene product from Mycobacterium tuberculosis==
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The line below this paragraph, containing "STRUCTURE_1nfr", creates the "Structure Box" on the page.
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<StructureSection load='1nfr' size='340' side='right'caption='[[1nfr]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nfr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NFR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NFR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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{{STRUCTURE_1nfr| PDB=1nfr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nfr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nfr OCA], [https://pdbe.org/1nfr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nfr RCSB], [https://www.ebi.ac.uk/pdbsum/1nfr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nfr ProSAT]</span></td></tr>
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</table>
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===Rv2002 gene product from Mycobacterium tuberculosis===
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== Function ==
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[https://www.uniprot.org/uniprot/HSD_MYCTU HSD_MYCTU]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12524453}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12524453 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nf/1nfr_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12524453}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1NFR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NFR OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nfr ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis., Yang JK, Park MS, Waldo GS, Suh SW, Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):455-60. Epub 2003 Jan 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12524453 12524453]
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Single protein]]
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[[Category: Park MS]]
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[[Category: Park, M S.]]
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[[Category: Suh SW]]
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[[Category: Suh, S W.]]
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[[Category: Waldo GS]]
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
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[[Category: Yang JK]]
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[[Category: Waldo, G S.]]
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[[Category: Yang, J K.]]
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[[Category: Directed evolution]]
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[[Category: Gfp]]
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[[Category: Hydroxysteroid dehydrogenase]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Sdr]]
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[[Category: Structural genomic]]
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[[Category: Tb structural genomics consortium]]
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[[Category: Tbsgc]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:11:23 2008''
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Current revision

Rv2002 gene product from Mycobacterium tuberculosis

PDB ID 1nfr

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