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1nkr

From Proteopedia

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{{Seed}}
 
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[[Image:1nkr.png|left|200px]]
 
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<!--
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==INHIBITORY RECEPTOR (P58-CL42) FOR HUMAN NATURAL KILLER CELLS==
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The line below this paragraph, containing "STRUCTURE_1nkr", creates the "Structure Box" on the page.
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<StructureSection load='1nkr' size='340' side='right'caption='[[1nkr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nkr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NKR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nkr OCA], [https://pdbe.org/1nkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nkr RCSB], [https://www.ebi.ac.uk/pdbsum/1nkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nkr ProSAT]</span></td></tr>
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{{STRUCTURE_1nkr| PDB=1nkr | SCENE= }}
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</table>
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== Function ==
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===INHIBITORY RECEPTOR (P58-CL42) FOR HUMAN NATURAL KILLER CELLS===
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[https://www.uniprot.org/uniprot/KI2L1_HUMAN KI2L1_HUMAN] Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.<ref>PMID:18604210</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_9288975}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 9288975 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/1nkr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_9288975}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nkr ConSurf].
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1NKR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKR OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors., Fan QR, Mosyak L, Winter CC, Wagtmann N, Long EO, Wiley DC, Nature. 1997 Sep 4;389(6646):96-100. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9288975 9288975]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Fan, Q R.]]
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[[Category: Fan QR]]
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[[Category: Long, E O.]]
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[[Category: Long EO]]
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[[Category: Mosyak, L.]]
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[[Category: Mosyak L]]
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[[Category: Wagtmann, N.]]
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[[Category: Wagtmann N]]
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[[Category: Wiley, D C.]]
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[[Category: Wiley DC]]
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[[Category: Winter, C C.]]
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[[Category: Winter CC]]
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[[Category: Immunoglobulin fold]]
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[[Category: Immunological receptor]]
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[[Category: Inhibitory receptor]]
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[[Category: Natural killer cell]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 10:56:29 2008''
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Current revision

INHIBITORY RECEPTOR (P58-CL42) FOR HUMAN NATURAL KILLER CELLS

PDB ID 1nkr

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