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1noz

From Proteopedia

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[[Image:1noz.png|left|200px]]
 
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{{STRUCTURE_1noz| PDB=1noz | SCENE= }}
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==T4 DNA POLYMERASE FRAGMENT (RESIDUES 1-388) AT 110K==
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<StructureSection load='1noz' size='340' side='right'caption='[[1noz]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===T4 DNA POLYMERASE FRAGMENT (RESIDUES 1-388) AT 110K===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1noz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NOZ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8679562}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1noz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1noz OCA], [https://pdbe.org/1noz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1noz RCSB], [https://www.ebi.ac.uk/pdbsum/1noz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1noz ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1noz]] is a 2 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NOZ OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/DPOL_BPT4 DPOL_BPT4] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/no/1noz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1noz ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[DNA polymerase|DNA polymerase]]
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:008679562</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
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[[Category: Escherichia virus T4]]
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Enterobacteria phage t4]]
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[[Category: Konigsberg WH]]
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[[Category: Konigsberg, W H.]]
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[[Category: Lin TC]]
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[[Category: Lin, T C.]]
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[[Category: Steitz TA]]
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[[Category: Steitz, T A.]]
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[[Category: Wang J]]
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[[Category: Wang, J.]]
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[[Category: Yu P]]
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[[Category: Yu, P.]]
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[[Category: Dna-binding]]
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[[Category: Exonuclease]]
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[[Category: Nucleotidyltransferase]]
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Current revision

T4 DNA POLYMERASE FRAGMENT (RESIDUES 1-388) AT 110K

PDB ID 1noz

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