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1nu0

From Proteopedia

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[[Image:1nu0.jpg|left|200px]]
 
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{{Structure
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==Structure of the double mutant (L6M; F134M, SeMet form) of yqgF from Escherichia coli, a hypothetical protein==
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|PDB= 1nu0 |SIZE=350|CAPTION= <scene name='initialview01'>1nu0</scene>, resolution 1.6&Aring;
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<StructureSection load='1nu0' size='340' side='right'caption='[[1nu0]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1nu0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NU0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NU0 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= YQGF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nu0 OCA], [https://pdbe.org/1nu0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nu0 RCSB], [https://www.ebi.ac.uk/pdbsum/1nu0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nu0 ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1nmn|1nmn]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nu0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nu0 OCA], [http://www.ebi.ac.uk/pdbsum/1nu0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nu0 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/YQGF_ECOLI YQGF_ECOLI] Involved in the processing of the 5'-end of pre-16S rRNA during 70S ribosome maturation (processing does not occur on total cellular RNA off the ribosome); may be a nuclease (PubMed:25545592). A temperature-sensitive yqgF mutant no longer grows when Rho or NusA are overproduced, and has reduced transcription of genes encoded downstream of Rho terminators; transcription increases again in the presence of the Rho inhibitor bicylomycin (PubMed:22353788).<ref>PMID:22353788</ref> <ref>PMID:25545592</ref>
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== Evolutionary Conservation ==
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'''Structure of the double mutant (L6M; F134M, SeMet form) of yqgF from Escherichia coli, a hypothetical protein'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nu/1nu0_consurf.spt"</scriptWhenChecked>
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1NU0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NU0 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nu0 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Galkin, A.]]
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[[Category: Galkin A]]
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[[Category: Herzberg, O.]]
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[[Category: Herzberg O]]
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[[Category: Howard, A.]]
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[[Category: Howard A]]
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[[Category: Krajewski, W.]]
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[[Category: Krajewski W]]
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[[Category: S2F, Structure 2.Function Project.]]
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[[Category: Sarikaya E]]
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[[Category: Sarikaya, E.]]
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[[Category: hypothetical protein]]
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[[Category: s2f]]
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[[Category: structural genomic]]
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[[Category: structure 2 function project]]
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[[Category: yqgf]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:35:29 2008''
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Current revision

Structure of the double mutant (L6M; F134M, SeMet form) of yqgF from Escherichia coli, a hypothetical protein

PDB ID 1nu0

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OCA

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