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1nz0

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{{Seed}}
 
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[[Image:1nz0.png|left|200px]]
 
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==RNASE P PROTEIN FROM THERMOTOGA MARITIMA==
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The line below this paragraph, containing "STRUCTURE_1nz0", creates the "Structure Box" on the page.
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<StructureSection load='1nz0' size='340' side='right'caption='[[1nz0]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1nz0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NZ0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1nz0| PDB=1nz0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nz0 OCA], [https://pdbe.org/1nz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nz0 RCSB], [https://www.ebi.ac.uk/pdbsum/1nz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nz0 ProSAT], [https://www.topsan.org/Proteins/BSGC/1nz0 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNPA_THEMA RNPA_THEMA] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nz/1nz0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nz0 ConSurf].
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<div style="clear:both"></div>
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===RNASE P PROTEIN FROM THERMOTOGA MARITIMA===
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12799461}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12799461 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12799461}}
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==About this Structure==
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1NZ0 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZ0 OCA].
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==Reference==
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High-resolution structure of RNase P protein from Thermotoga maritima., Kazantsev AV, Krivenko AA, Harrington DJ, Carter RJ, Holbrook SR, Adams PD, Pace NR, Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7497-502. Epub 2003 Jun 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12799461 12799461]
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[[Category: Ribonuclease P]]
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Adams, P D.]]
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[[Category: Adams PD]]
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[[Category: BSGC, Berkeley Structural Genomics Center.]]
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[[Category: Carter RJ]]
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[[Category: Carter, R J.]]
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[[Category: Harrington DJ]]
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[[Category: Harrington, D J.]]
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[[Category: Holbrook SR]]
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[[Category: Holbrook, S R.]]
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[[Category: Kazantsev AV]]
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[[Category: Kazantsev, A V.]]
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[[Category: Krivenko AA]]
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[[Category: Krivenko, A A.]]
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[[Category: Pace NR]]
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[[Category: Pace, N R.]]
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[[Category: Alfa-beta sandwich]]
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[[Category: Berkeley structural genomics center]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: Dimer]]
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[[Category: Endonuclease]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Rnase]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 14:04:03 2008''
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Current revision

RNASE P PROTEIN FROM THERMOTOGA MARITIMA

PDB ID 1nz0

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