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1occ

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[[Image:1occ.png|left|200px]]
 
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{{STRUCTURE_1occ| PDB=1occ | SCENE= }}
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==STRUCTURE OF BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE==
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<StructureSection load='1occ' size='340' side='right'caption='[[1occ]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===STRUCTURE OF BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1occ]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OCC FirstGlance]. <br>
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{{ABSTRACT_PUBMED_8638158}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=HEA:HEME-A'>HEA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1occ FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1occ OCA], [https://pdbe.org/1occ PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1occ RCSB], [https://www.ebi.ac.uk/pdbsum/1occ PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1occ ProSAT]</span></td></tr>
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[[1occ]] is a 26 chain structure of [[Cytochrome c oxidase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCC OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/COX1_BOVIN COX1_BOVIN] Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oc/1occ_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1occ ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Cytochrome c oxidase|Cytochrome c oxidase]]
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*[[Cytochrome c oxidase 3D structures|Cytochrome c oxidase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:008638158</ref><ref group="xtra">PMID:009922138</ref><ref group="xtra">PMID:010089392</ref><references group="xtra"/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Cytochrome-c oxidase]]
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[[Category: Large Structures]]
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[[Category: Aoyama, H.]]
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[[Category: Aoyama H]]
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[[Category: Nakashima, R.]]
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[[Category: Nakashima R]]
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[[Category: Shinzawa-Itoh, K.]]
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[[Category: Shinzawa-Itoh K]]
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[[Category: Tomizaki, T.]]
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[[Category: Tomizaki T]]
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[[Category: Tsukihara, T.]]
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[[Category: Tsukihara T]]
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[[Category: Yamaguchi, H.]]
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[[Category: Yamaguchi H]]
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[[Category: Yamashita, E.]]
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[[Category: Yamashita E]]
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[[Category: Yaono, R.]]
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[[Category: Yaono R]]
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[[Category: Yoshikawa, S.]]
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[[Category: Yoshikawa S]]
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[[Category: Cytochrome c oxidase]]
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Current revision

STRUCTURE OF BOVINE HEART CYTOCHROME C OXIDASE AT THE FULLY OXIDIZED STATE

PDB ID 1occ

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