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1od1

From Proteopedia

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{{Seed}}
 
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[[Image:1od1.png|left|200px]]
 
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==Endothiapepsin PD135,040 complex==
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The line below this paragraph, containing "STRUCTURE_1od1", creates the "Structure Box" on the page.
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<StructureSection load='1od1' size='340' side='right'caption='[[1od1]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1od1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OD1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0QS:N~2~-[(2R)-2-BENZYL-3-(TERT-BUTYLSULFONYL)PROPANOYL]-N-{(1R)-1-(CYCLOHEXYLMETHYL)-3,3-DIFLUORO-2,2-DIHYDROXY-4-[(2-MORPHOLIN-4-YLETHYL)AMINO]-4-OXOBUTYL}-3-(1H-IMIDAZOL-3-IUM-4-YL)-L-ALANINAMIDE'>0QS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1od1| PDB=1od1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1od1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1od1 OCA], [https://pdbe.org/1od1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1od1 RCSB], [https://www.ebi.ac.uk/pdbsum/1od1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1od1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/od/1od1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1od1 ConSurf].
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<div style="clear:both"></div>
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===ENDOTHIAPEPSIN PD135,040 COMPLEX===
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==See Also==
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*[[Pepsin|Pepsin]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12777758}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12777758 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12777758}}
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==About this Structure==
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1OD1 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OD1 OCA].
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==Reference==
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The structure of endothiapepsin complexed with the gem-diol inhibitor PD-135,040 at 1.37 A., Coates L, Erskine PT, Mall S, Williams PA, Gill RS, Wood SP, Cooper JB, Acta Crystallogr D Biol Crystallogr. 2003 Jun;59(Pt 6):978-81. Epub 2003, May 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12777758 12777758]
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[[Category: Cryphonectria parasitica]]
[[Category: Cryphonectria parasitica]]
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[[Category: Endothiapepsin]]
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[[Category: Large Structures]]
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[[Category: Protein complex]]
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[[Category: Coates L]]
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[[Category: Coates, L.]]
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[[Category: Cooper JB]]
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[[Category: Cooper, J B.]]
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[[Category: Erskine PT]]
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[[Category: Erskine, P T.]]
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[[Category: Gill RS]]
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[[Category: Gill, R S.]]
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[[Category: Mall S]]
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[[Category: Mall, S.]]
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[[Category: Wood SP]]
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[[Category: Wood, S P.]]
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[[Category: Hydrolase,acid proteinase,inhibitor,aspartyl protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:04:09 2008''
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Current revision

Endothiapepsin PD135,040 complex

PDB ID 1od1

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