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1ohs

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[[Image:1ohs.gif|left|200px]]<br /><applet load="1ohs" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1ohs, resolution 1.7&Aring;" />
 
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'''CRYSTAL STRUCTURE OF 5-3-KETOSTEROID ISOMERASE MUTANT Y14F/ D38N FROM PSEUDOMONAS TESTOSTERONI COMPLEXED WITH ANDROSTANEDIONE'''<br />
 
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==About this Structure==
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==CRYSTAL STRUCTURE OF 5-3-KETOSTEROID ISOMERASE MUTANT Y14F/D38N FROM PSEUDOMONAS TESTOSTERONI COMPLEXED WITH ANDROSTANEDIONE==
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1OHS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Comamonas_testosteroni Comamonas testosteroni] with 5SD as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Steroid_Delta-isomerase Steroid Delta-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.1 5.3.3.1] Known structural/functional Site: <scene name='pdbsite=AC1:5sd Binding Site For Chain C'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OHS OCA].
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<StructureSection load='1ohs' size='340' side='right'caption='[[1ohs]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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[[Category: Comamonas testosteroni]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1ohs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Comamonas_testosteroni Comamonas testosteroni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OHS FirstGlance]. <br>
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[[Category: Steroid Delta-isomerase]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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[[Category: Byun, M.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5SD:5ALPHA-ANDROSTAN-3,17-DIONE'>5SD</scene></td></tr>
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[[Category: Kim, M.S.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ohs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ohs OCA], [https://pdbe.org/1ohs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ohs RCSB], [https://www.ebi.ac.uk/pdbsum/1ohs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ohs ProSAT]</span></td></tr>
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[[Category: Oh, B.H.]]
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</table>
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[[Category: 5SD]]
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== Function ==
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[[Category: androstanedione]]
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[https://www.uniprot.org/uniprot/SDIS_COMTE SDIS_COMTE]
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[[Category: inhibitor]]
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== Evolutionary Conservation ==
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[[Category: isomerase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oh/1ohs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ohs ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 17:44:18 2007''
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==See Also==
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*[[Ketosteroid Isomerase|Ketosteroid Isomerase]]
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__TOC__
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</StructureSection>
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[[Category: Comamonas testosteroni]]
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[[Category: Large Structures]]
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[[Category: Byun M]]
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[[Category: Kim M-S]]
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[[Category: Oh B-H]]

Current revision

CRYSTAL STRUCTURE OF 5-3-KETOSTEROID ISOMERASE MUTANT Y14F/D38N FROM PSEUDOMONAS TESTOSTERONI COMPLEXED WITH ANDROSTANEDIONE

PDB ID 1ohs

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