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1onj

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Current revision (05:49, 17 April 2024) (edit) (undo)
 
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{{Seed}}
 
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[[Image:1onj.png|left|200px]]
 
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<!--
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==Crystal structure of Atratoxin-b from Chinese cobra venom of Naja atra==
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The line below this paragraph, containing "STRUCTURE_1onj", creates the "Structure Box" on the page.
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<StructureSection load='1onj' size='340' side='right'caption='[[1onj]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1onj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_atra Naja atra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ONJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.555&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1onj| PDB=1onj | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1onj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1onj OCA], [https://pdbe.org/1onj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1onj RCSB], [https://www.ebi.ac.uk/pdbsum/1onj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1onj ProSAT]</span></td></tr>
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</table>
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===Crystal structure of Atratoxin-b from Chinese cobra venom of Naja atra===
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== Function ==
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[https://www.uniprot.org/uniprot/3S1CC_NAJAT 3S1CC_NAJAT] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission. Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Has a lower toxicity than cobrotoxin.<ref>PMID:9498573</ref>
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12777767}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12777767 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/1onj_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12777767}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1ONJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Naja_atra Naja atra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONJ OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1onj ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:12777767</ref><references group="xtra"/>
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Naja atra]]
[[Category: Naja atra]]
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[[Category: Deng, W.]]
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[[Category: Deng W]]
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[[Category: Fan, R.]]
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[[Category: Fan R]]
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[[Category: Lou, X.]]
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[[Category: Lou X]]
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[[Category: Lu, W.]]
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[[Category: Lu W]]
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[[Category: Niu, L.]]
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[[Category: Niu L]]
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[[Category: Pan, G.]]
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[[Category: Pan G]]
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[[Category: Rao, P.]]
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[[Category: Rao P]]
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[[Category: Teng, M.]]
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[[Category: Teng M]]
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[[Category: Tu, X.]]
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[[Category: Tu X]]
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[[Category: Xu, C.]]
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[[Category: Xu C]]
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[[Category: Beta-turn-beta]]
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[[Category: Three-finger protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:23:05 2009''
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Current revision

Crystal structure of Atratoxin-b from Chinese cobra venom of Naja atra

PDB ID 1onj

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