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1or0

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{{Seed}}
 
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[[Image:1or0.png|left|200px]]
 
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<!--
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==Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation==
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The line below this paragraph, containing "STRUCTURE_1or0", creates the "Structure Box" on the page.
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<StructureSection load='1or0' size='340' side='right'caption='[[1or0]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1or0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._SY-77-1 Pseudomonas sp. SY-77-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OR0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1or0| PDB=1or0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1or0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1or0 OCA], [https://pdbe.org/1or0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1or0 RCSB], [https://www.ebi.ac.uk/pdbsum/1or0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1or0 ProSAT]</span></td></tr>
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</table>
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===Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation===
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== Function ==
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[https://www.uniprot.org/uniprot/G7AC_PSEU7 G7AC_PSEU7] Catalyzes the deacylation of 7 beta-(4-carboxybutanamido)cephalosporanic acid (glutaryl-7-aminocephalosporanic acid or GL-7-ACA) to 7-aminocephalosporanic acid (7-ACA).<ref>PMID:2993240</ref>
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12680762}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12680762 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/or/1or0_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12680762}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1OR0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_sp._sy-77 Pseudomonas sp. sy-77]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OR0 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1or0 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structures of glutaryl 7-aminocephalosporanic acid acylase: insight into autoproteolytic activation., Kim JK, Yang IS, Rhee S, Dauter Z, Lee YS, Park SS, Kim KH, Biochemistry. 2003 Apr 15;42(14):4084-93. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12680762 12680762]
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<references/>
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[[Category: Protein complex]]
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__TOC__
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[[Category: Pseudomonas sp. sy-77]]
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</StructureSection>
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[[Category: Dauter, Z.]]
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[[Category: Large Structures]]
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[[Category: Kim, J K.]]
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[[Category: Pseudomonas sp. SY-77-1]]
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[[Category: Kim, K H.]]
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[[Category: Dauter Z]]
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[[Category: Lee, Y S.]]
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[[Category: Kim JK]]
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[[Category: Park, S S.]]
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[[Category: Kim KH]]
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[[Category: Rhee, S.]]
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[[Category: Lee YS]]
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[[Category: Yang, I S.]]
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[[Category: Park SS]]
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[[Category: Glutaryl 7-aminocephalosporanic acid]]
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[[Category: Rhee S]]
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[[Category: Glutaryl 7-aminocephalosporanic acid acylase]]
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[[Category: Yang IS]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:10:42 2008''
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Current revision

Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation

PDB ID 1or0

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