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1ou9

From Proteopedia

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{{Seed}}
 
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[[Image:1ou9.png|left|200px]]
 
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==Structure of SspB, a AAA+ protease delivery protein==
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The line below this paragraph, containing "STRUCTURE_1ou9", creates the "Structure Box" on the page.
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<StructureSection load='1ou9' size='340' side='right'caption='[[1ou9]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ou9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OU9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1ou9| PDB=1ou9 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ou9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ou9 OCA], [https://pdbe.org/1ou9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ou9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ou9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ou9 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SSPB_HAEIN SSPB_HAEIN] Enhances recognition of ssrA-tagged proteins by the ClpX-ClpP protease; the ssrA degradation tag (AANDENYALAA) is added trans-translationally to proteins that are stalled on the ribosome, freeing the ribosome and targeting stalled peptides for degradation. SspB activates the ATPase activity of ClpX. Seems to act in concert with SspA in the regulation of several proteins during exponential and stationary-phase growth (By similarity). Also stimulates degradation of the N-terminus of RseA (residues 1-108, alone or in complex with sigma-E) by ClpX-ClpP in a non-ssrA-mediated fashion (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ou/1ou9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ou9 ConSurf].
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<div style="clear:both"></div>
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===Structure of SspB, a AAA+ protease delivery protein===
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==See Also==
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*[[Stringent starvation protein 3D structures|Stringent starvation protein 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_14536076}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 14536076 is the PubMed ID number.
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{{ABSTRACT_PUBMED_14536076}}
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==About this Structure==
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1OU9 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OU9 OCA].
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==Reference==
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<ref group="xtra">PMID:14536076</ref><references group="xtra"/>
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[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
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[[Category: Baker, T A.]]
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[[Category: Large Structures]]
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[[Category: Grant, R A.]]
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[[Category: Baker TA]]
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[[Category: Levchenko, I.]]
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[[Category: Grant RA]]
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[[Category: Sauer, R T.]]
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[[Category: Levchenko I]]
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[[Category: Wah, D A.]]
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[[Category: Sauer RT]]
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[[Category: Homodimer]]
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[[Category: Wah DA]]
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[[Category: Ssra peptide-binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:59:39 2009''
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Current revision

Structure of SspB, a AAA+ protease delivery protein

PDB ID 1ou9

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