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1oxw

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{{Seed}}
 
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[[Image:1oxw.png|left|200px]]
 
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<!--
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==The Crystal Structure of SeMet Patatin==
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The line below this paragraph, containing "STRUCTURE_1oxw", creates the "Structure Box" on the page.
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<StructureSection load='1oxw' size='340' side='right'caption='[[1oxw]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1oxw]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Solanum_cardiophyllum Solanum cardiophyllum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OXW FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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-->
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1oxw| PDB=1oxw | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oxw OCA], [https://pdbe.org/1oxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oxw RCSB], [https://www.ebi.ac.uk/pdbsum/1oxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oxw ProSAT]</span></td></tr>
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</table>
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===The Crystal Structure of SeMet Patatin===
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== Function ==
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[https://www.uniprot.org/uniprot/PAT17_SOLCD PAT17_SOLCD]
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12779324}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12779324 is the PubMed ID number.
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<jmolCheckbox>
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-->
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ox/1oxw_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12779324}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1OXW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Solanum_cardiophyllum Solanum cardiophyllum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXW OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1oxw ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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The crystal structure, mutagenesis, and activity studies reveal that patatin is a lipid acyl hydrolase with a Ser-Asp catalytic dyad., Rydel TJ, Williams JM, Krieger E, Moshiri F, Stallings WC, Brown SM, Pershing JC, Purcell JP, Alibhai MF, Biochemistry. 2003 Jun 10;42(22):6696-708. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12779324 12779324]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
[[Category: Solanum cardiophyllum]]
[[Category: Solanum cardiophyllum]]
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[[Category: Alibhai, M F.]]
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[[Category: Alibhai MF]]
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[[Category: Brown, S M.]]
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[[Category: Brown SM]]
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[[Category: Krieger, E.]]
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[[Category: Krieger E]]
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[[Category: Moshiri, F.]]
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[[Category: Moshiri F]]
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[[Category: Pershing, J C.]]
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[[Category: Pershing JC]]
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[[Category: Purcell, J P.]]
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[[Category: Purcell JP]]
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[[Category: Rydel, T J.]]
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[[Category: Rydel TJ]]
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[[Category: Stallings, W C.]]
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[[Category: Stallings WC]]
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[[Category: Williams, J M.]]
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[[Category: Williams JM]]
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[[Category: Alpha/beta class fold with approximately three layer]]
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[[Category: Alpha/beta/alpha in content. possesses a central six-stranded beta sheet with alpha-helices front & back]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 09:19:27 2008''
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Current revision

The Crystal Structure of SeMet Patatin

PDB ID 1oxw

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