1p7a

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{{Seed}}
 
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[[Image:1p7a.png|left|200px]]
 
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==Solution Structure of the Third Zinc Finger from BKLF==
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The line below this paragraph, containing "STRUCTURE_1p7a", creates the "Structure Box" on the page.
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<StructureSection load='1p7a' size='340' side='right'caption='[[1p7a]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p7a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P7A FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1p7a| PDB=1p7a | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p7a OCA], [https://pdbe.org/1p7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p7a RCSB], [https://www.ebi.ac.uk/pdbsum/1p7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p7a ProSAT]</span></td></tr>
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</table>
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===Solution Stucture of the Third Zinc Finger from BKLF===
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== Function ==
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[https://www.uniprot.org/uniprot/KLF3_MOUSE KLF3_MOUSE] Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.<ref>PMID:8657145</ref> <ref>PMID:15684403</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12736264}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12736264 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p7/1p7a_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12736264}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1P7A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7A OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p7a ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions., Simpson RJ, Cram ED, Czolij R, Matthews JM, Crossley M, Mackay JP, J Biol Chem. 2003 Jul 25;278(30):28011-8. Epub 2003 May 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12736264 12736264]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Cram ED]]
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[[Category: Cram, E D.]]
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[[Category: Crossley M]]
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[[Category: Crossley, M.]]
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[[Category: Czolij R]]
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[[Category: Czolij, R.]]
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[[Category: Mackay JP]]
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[[Category: Mackay, J P.]]
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[[Category: Matthews JM]]
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[[Category: Matthews, J M.]]
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[[Category: Simpson RJY]]
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[[Category: Simpson, R J.Y.]]
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[[Category: Classical zinc finger]]
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[[Category: Kruppel-like]]
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[[Category: Transcription factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:21:35 2008''
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Current revision

Solution Structure of the Third Zinc Finger from BKLF

PDB ID 1p7a

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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