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1p7d

From Proteopedia

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{{Seed}}
 
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[[Image:1p7d.png|left|200px]]
 
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<!--
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==Crystal structure of the Lambda Integrase (residues 75-356) bound to DNA==
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The line below this paragraph, containing "STRUCTURE_1p7d", creates the "Structure Box" on the page.
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<StructureSection load='1p7d' size='340' side='right'caption='[[1p7d]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p7d]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P7D FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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{{STRUCTURE_1p7d| PDB=1p7d | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p7d OCA], [https://pdbe.org/1p7d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p7d RCSB], [https://www.ebi.ac.uk/pdbsum/1p7d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p7d ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VINT_LAMBD VINT_LAMBD] Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p7/1p7d_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p7d ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the Lambda Integrase (residues 75-356) bound to DNA===
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==See Also==
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*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12887904}}, adds the Publication Abstract to the page
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[[Category: Escherichia virus Lambda]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12887904 is the PubMed ID number.
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[[Category: Large Structures]]
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-->
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[[Category: Aihara H]]
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{{ABSTRACT_PUBMED_12887904}}
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[[Category: Ellenberger T]]
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[[Category: Kwon HJ]]
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==About this Structure==
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[[Category: Landy A]]
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1P7D is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P7D OCA].
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[[Category: Nunes-Duby SE]]
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==Reference==
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<ref group="xtra">PMID:12887904</ref><references group="xtra"/>
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[[Category: Enterobacteria phage lambda]]
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[[Category: Aihara, H.]]
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[[Category: Ellenberger, T.]]
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[[Category: Kwon, H J.]]
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[[Category: Landy, A.]]
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[[Category: Nunes-Duby, S E.]]
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[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:15:30 2009''
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Current revision

Crystal structure of the Lambda Integrase (residues 75-356) bound to DNA

PDB ID 1p7d

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