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1p8b

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{{Seed}}
 
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[[Image:1p8b.png|left|200px]]
 
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==SOLUTION STRUCTURE OF PA1B, A 37-AMINO ACID INSECTICIDAL PROTEIN EXTRACTED FROM PEA SEEDS (PISUM SATIVUM)==
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The line below this paragraph, containing "STRUCTURE_1p8b", creates the "Structure Box" on the page.
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<StructureSection load='1p8b' size='340' side='right'caption='[[1p8b]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1p8b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P8B FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p8b OCA], [https://pdbe.org/1p8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p8b RCSB], [https://www.ebi.ac.uk/pdbsum/1p8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p8b ProSAT]</span></td></tr>
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{{STRUCTURE_1p8b| PDB=1p8b | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ALB1F_PEA ALB1F_PEA] PA1b binds to basic 7S globulin (BG) and stimulates its phosphorylation activity. Involved in the signal transduction system to regulate the growth and differentiation as a hormone peptide (By similarity). Toxic to various insects through binding to a high affinity binding site in the insect gut.<ref>PMID:12755698</ref> [REFERENCE:2]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p8/1p8b_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p8b ConSurf].
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<div style="clear:both"></div>
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===SOLUTION STRUCTURE OF PA1B, A 37-AMINO ACID INSECTICIDAL PROTEIN EXTRACTED FROM PEA SEEDS (PISUM SATIVUM)===
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==See Also==
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*[[Albumin 3D structures|Albumin 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_14556622}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 14556622 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_14556622}}
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==About this Structure==
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1P8B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P8B OCA].
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==Reference==
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PA1b, an insecticidal protein extracted from pea seeds (Pisum sativum): 1H-2-D NMR study and molecular modeling., Jouvensal L, Quillien L, Ferrasson E, Rahbe Y, Gueguen J, Vovelle F, Biochemistry. 2003 Oct 21;42(41):11915-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14556622 14556622]
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[[Category: Pisum sativum]]
[[Category: Pisum sativum]]
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[[Category: Single protein]]
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[[Category: Ferrasson E]]
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[[Category: Ferrasson, E.]]
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[[Category: Gueguen J]]
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[[Category: Gueguen, J.]]
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[[Category: Jouvensal L]]
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[[Category: Jouvensal, L.]]
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[[Category: Quillien L]]
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[[Category: Quillien, L.]]
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[[Category: Rahbe Y]]
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[[Category: Rahbe, Y.]]
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[[Category: Vovelle F]]
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[[Category: Vovelle, F.]]
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[[Category: Inhibitor cystine-knot]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 04:59:09 2008''
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Current revision

SOLUTION STRUCTURE OF PA1B, A 37-AMINO ACID INSECTICIDAL PROTEIN EXTRACTED FROM PEA SEEDS (PISUM SATIVUM)

PDB ID 1p8b

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