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1p91

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[[Image:1p91.png|left|200px]]
 
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{{STRUCTURE_1p91| PDB=1p91 | SCENE= }}
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==Crystal Structure of RlmA(I) enzyme: 23S rRNA n1-G745 methyltransferase (NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER19)==
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<StructureSection load='1p91' size='340' side='right'caption='[[1p91]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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===Crystal Structure of RlmA(I) enzyme: 23S rRNA n1-G745 methyltransferase (NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER19)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1p91]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P91 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P91 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_14999102}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p91 OCA], [https://pdbe.org/1p91 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p91 RCSB], [https://www.ebi.ac.uk/pdbsum/1p91 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p91 ProSAT], [https://www.topsan.org/Proteins/NESGC/1p91 TOPSAN]</span></td></tr>
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[[1p91]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P91 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/RLMA_ECOLI RLMA_ECOLI] Specifically methylates the guanosine in position 745 of 23S rRNA.<ref>PMID:9440525</ref>
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<ref group="xtra">PMID:014999102</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p9/1p91_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1p91 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Acton, T.]]
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[[Category: Large Structures]]
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[[Category: Arnold, E.]]
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[[Category: Acton T]]
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[[Category: Das, K.]]
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[[Category: Arnold E]]
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[[Category: Montelione, G.]]
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[[Category: Das K]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione G]]
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[[Category: 23s rrna]]
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[[Category: Er19]]
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[[Category: G745]]
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[[Category: Methyltransferase]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Rlma]]
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[[Category: Rrma]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of RlmA(I) enzyme: 23S rRNA n1-G745 methyltransferase (NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER19)

PDB ID 1p91

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