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1psu

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[[Image:1psu.png|left|200px]]
 
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{{STRUCTURE_1psu| PDB=1psu | SCENE= }}
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==Structure of the E. coli PaaI protein from the phyenylacetic acid degradation operon==
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<StructureSection load='1psu' size='340' side='right'caption='[[1psu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===Structure of the E. coli PaaI protein from the phyenylacetic acid degradation operon===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1psu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PSU FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[1psu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PSU OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1psu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1psu OCA], [https://pdbe.org/1psu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1psu RCSB], [https://www.ebi.ac.uk/pdbsum/1psu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1psu ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1psu TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PAAI_ECOLI PAAI_ECOLI] Thioesterase with a preference for ring-hydroxylated phenylacetyl-CoA esters. Hydrolyzes 3,4-dihydroxyphenylacetyl-CoA, 3-hydroxyphenylacetyl-CoA and 4-hydroxyphenylacetyl-CoA. Inactive towards 4-hydroxybenzoyl-CoA and 4-hydroxyphenacyl-CoA.<ref>PMID:9748275</ref> <ref>PMID:16464851</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/1psu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1psu ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Buglino, J.]]
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[[Category: Large Structures]]
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[[Category: Burley, S K.]]
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[[Category: Buglino J]]
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[[Category: Kniewel, R.]]
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[[Category: Burley SK]]
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[[Category: Lima, C D.]]
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[[Category: Kniewel R]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Lima CD]]
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[[Category: Solorzano, V.]]
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[[Category: Solorzano V]]
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[[Category: Wu, J.]]
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[[Category: Wu J]]
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[[Category: Degradation]]
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[[Category: Hydrolase]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: Nysgxrc]]
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[[Category: Operon]]
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[[Category: Phenylacetic acid]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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[[Category: T820]]
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Current revision

Structure of the E. coli PaaI protein from the phyenylacetic acid degradation operon

PDB ID 1psu

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