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1pzn

From Proteopedia

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{{Seed}}
 
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[[Image:1pzn.png|left|200px]]
 
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<!--
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==Rad51 (RadA)==
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The line below this paragraph, containing "STRUCTURE_1pzn", creates the "Structure Box" on the page.
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<StructureSection load='1pzn' size='340' side='right'caption='[[1pzn]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1pzn]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. The April 2014 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''RecA and Rad51'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2014_4 10.2210/rcsb_pdb/mom_2014_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PZN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1pzn| PDB=1pzn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pzn OCA], [https://pdbe.org/1pzn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pzn RCSB], [https://www.ebi.ac.uk/pdbsum/1pzn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pzn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pz/1pzn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pzn ConSurf].
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<div style="clear:both"></div>
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===Rad51 (RadA)===
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==See Also==
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*[[Resolvase 3D structures|Resolvase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12941707 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12941707}}
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==About this Structure==
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1PZN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PZN OCA].
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==Reference==
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Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2., Shin DS, Pellegrini L, Daniels DS, Yelent B, Craig L, Bates D, Yu DS, Shivji MK, Hitomi C, Arvai AS, Volkmann N, Tsuruta H, Blundell TL, Venkitaraman AR, Tainer JA, EMBO J. 2003 Sep 1;22(17):4566-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12941707 12941707]
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[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
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[[Category: Single protein]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Shin, D S.]]
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[[Category: RecA and Rad51]]
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[[Category: Tainer, J A.]]
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[[Category: Shin DS]]
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[[Category: Atpase]]
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[[Category: Tainer JA]]
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[[Category: Dna recombination]]
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[[Category: Dna repair]]
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[[Category: Helix-hairpin-helix]]
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[[Category: Heptamer]]
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[[Category: Heptameric ring]]
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[[Category: Homologous recombination]]
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[[Category: Oligomer]]
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[[Category: Rad51 polymerization motif]]
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[[Category: Ring]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:01:13 2008''
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Current revision

Rad51 (RadA)

PDB ID 1pzn

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