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1q8h

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{{Seed}}
 
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[[Image:1q8h.png|left|200px]]
 
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<!--
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==Crystal structure of porcine osteocalcin==
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The line below this paragraph, containing "STRUCTURE_1q8h", creates the "Structure Box" on the page.
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<StructureSection load='1q8h' size='340' side='right'caption='[[1q8h]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1q8h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q8H FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr>
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{{STRUCTURE_1q8h| PDB=1q8h | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q8h OCA], [https://pdbe.org/1q8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q8h RCSB], [https://www.ebi.ac.uk/pdbsum/1q8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q8h ProSAT]</span></td></tr>
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</table>
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===Crystal structure of porcine osteocalcin===
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== Function ==
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[https://www.uniprot.org/uniprot/OSTCN_PIG OSTCN_PIG] Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_14586470}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 14586470 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q8/1q8h_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_14586470}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1Q8H is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q8H OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q8h ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Bone recognition mechanism of porcine osteocalcin from crystal structure., Hoang QQ, Sicheri F, Howard AJ, Yang DS, Nature. 2003 Oct 30;425(6961):977-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14586470 14586470]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Hoang, Q Q.]]
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[[Category: Hoang QQ]]
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[[Category: Howard, A J.]]
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[[Category: Howard AJ]]
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[[Category: Sicheri, F.]]
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[[Category: Sicheri F]]
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[[Category: Yang, D S.]]
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[[Category: Yang DS]]
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[[Category: Bone gla protein]]
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[[Category: Calcium binding protein]]
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[[Category: Helix-turn-helix-turn-helix]]
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[[Category: Hydroxyapatite crystal surface binding protein]]
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[[Category: Paper-clip]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:40:50 2008''
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Current revision

Crystal structure of porcine osteocalcin

PDB ID 1q8h

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