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1qkr

From Proteopedia

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{{Seed}}
 
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[[Image:1qkr.png|left|200px]]
 
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==Crystal structure of the vinculin tail and a pathway for activation==
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The line below this paragraph, containing "STRUCTURE_1qkr", creates the "Structure Box" on the page.
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<StructureSection load='1qkr' size='340' side='right'caption='[[1qkr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qkr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QKR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1qkr| PDB=1qkr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qkr OCA], [https://pdbe.org/1qkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qkr RCSB], [https://www.ebi.ac.uk/pdbsum/1qkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qkr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VINC_CHICK VINC_CHICK] Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.<ref>PMID:15229287</ref> <ref>PMID:20584916</ref> <ref>PMID:20086044</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qk/1qkr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qkr ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF THE VINCULIN TAIL AND A PATHWAY FOR ACTIVATION===
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==See Also==
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*[[Vinculin 3D structures|Vinculin 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10612396}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10612396 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_10612396}}
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==About this Structure==
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1QKR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QKR OCA].
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==Reference==
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Crystal structure of the vinculin tail suggests a pathway for activation., Bakolitsa C, de Pereda JM, Bagshaw CR, Critchley DR, Liddington RC, Cell. 1999 Dec 10;99(6):603-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10612396 10612396]
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Bagshaw, C R.]]
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[[Category: Bagshaw CR]]
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[[Category: Bakolitsa, C.]]
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[[Category: Bakolitsa C]]
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[[Category: Critchley, D R.]]
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[[Category: Critchley DR]]
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[[Category: Liddington, R C.]]
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[[Category: De Pereda JM]]
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[[Category: Pereda, J M.De.]]
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[[Category: Liddington RC]]
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[[Category: Actin cytoskeleton]]
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[[Category: Cell adhesion]]
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[[Category: Helical bundle]]
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[[Category: Lipid binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 23:00:12 2008''
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Current revision

Crystal structure of the vinculin tail and a pathway for activation

PDB ID 1qkr

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