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1qnc

From Proteopedia

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{{Seed}}
 
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[[Image:1qnc.png|left|200px]]
 
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==Crystal structure of the A(-31) Adenovirus major late promoter TATA box variant bound to wild-type TBP (Arabidopsis thaliana TBP isoform 2). TATA element recognition by the TATA box-binding protein has been conserved throughout evolution.==
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The line below this paragraph, containing "STRUCTURE_1qnc", creates the "Structure Box" on the page.
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<StructureSection load='1qnc' size='340' side='right'caption='[[1qnc]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qnc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QNC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qnc OCA], [https://pdbe.org/1qnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qnc RCSB], [https://www.ebi.ac.uk/pdbsum/1qnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qnc ProSAT]</span></td></tr>
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{{STRUCTURE_1qnc| PDB=1qnc | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TBP1_ARATH TBP1_ARATH] General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/1qnc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qnc ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF THE A(-31) ADENOVIRUS MAJOR LATE PROMOTER TATA BOX VARIANT BOUND TO WILD-TYPE TBP (ARABIDOPSIS THALIANA TBP ISOFORM 2). TATA ELEMENT RECOGNITION BY THE TATA BOX-BINDING PROTEIN HAS BEEN CONSERVED THROUGHOUT EVOLUTION===
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==See Also==
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*[[TATA-binding protein 3D structures|TATA-binding protein 3D structures]]
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*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_10617571}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 10617571 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10617571}}
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==About this Structure==
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1QNC is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QNC OCA].
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==Reference==
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<ref group="xtra">PMID:10617571</ref><references group="xtra"/>
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Burley, S K.]]
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[[Category: Large Structures]]
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[[Category: Kim, J L.]]
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[[Category: Burley SK]]
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[[Category: Kodadek, T.]]
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[[Category: Kim JL]]
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[[Category: Patikoglou, G A.]]
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[[Category: Kodadek T]]
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[[Category: Sun, L.]]
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[[Category: Patikoglou GA]]
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[[Category: Yang, S H.]]
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[[Category: Sun L]]
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[[Category: Tbp-tata element complex]]
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[[Category: Yang S-H]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:20:51 2009''
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Current revision

Crystal structure of the A(-31) Adenovirus major late promoter TATA box variant bound to wild-type TBP (Arabidopsis thaliana TBP isoform 2). TATA element recognition by the TATA box-binding protein has been conserved throughout evolution.

PDB ID 1qnc

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