This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1qns

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:05, 17 April 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1qns.png|left|200px]]
 
-
<!--
+
==The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5==
-
The line below this paragraph, containing "STRUCTURE_1qns", creates the "Structure Box" on the page.
+
<StructureSection load='1qns' size='340' side='right'caption='[[1qns]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1qns]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoderma_reesei Trichoderma reesei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QNS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QNS FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-
{{STRUCTURE_1qns| PDB=1qns | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qns OCA], [https://pdbe.org/1qns PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qns RCSB], [https://www.ebi.ac.uk/pdbsum/1qns PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qns ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/MANA_HYPJR MANA_HYPJR] Endo-1,4-mannanase that catalyzes the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans and heteromannans. It is a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans. Active against locust bean gum and ivory nut mannan, releasing mainly tri- and disaccharides (PubMed:7793911, Ref.3, Ref.4, PubMed:8529653). Also has transglycosylation activity. Transglycosylation of two mannotrioses into a mannohexaose is the major transglycosylation route (PubMed:8529653, Ref.7, PubMed:24950755).<ref>PMID:24950755</ref> <ref>PMID:7793911</ref> <ref>PMID:8529653</ref> [PROSITE-ProRule:PRU00597][SAM:MobiDB-lite]<ref>PMID:24950755</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qn/1qns_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qns ConSurf].
 +
<div style="clear:both"></div>
-
===THE 3-D STRUCTURE OF A TRICHODERMA REESEI B-MANNANASE FROM GLYCOSIDE HYDROLASE FAMILY 5===
+
==See Also==
-
 
+
*[[Mannosidase 3D structures|Mannosidase 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_10666621}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 10666621 is the PubMed ID number.
+
</StructureSection>
-
-->
+
[[Category: Large Structures]]
-
{{ABSTRACT_PUBMED_10666621}}
+
-
 
+
-
==About this Structure==
+
-
1QNS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Hypocrea_jecorina Hypocrea jecorina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QNS OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:10666621</ref><references group="xtra"/>
+
-
[[Category: Hypocrea jecorina]]
+
-
[[Category: Mannan endo-1,4-beta-mannosidase]]
+
-
[[Category: Murshudov, G.]]
+
-
[[Category: Penttila, M.]]
+
-
[[Category: Sabini, E.]]
+
-
[[Category: Schubert, H.]]
+
-
[[Category: Siika-Aho, M.]]
+
-
[[Category: Wilson, K S.]]
+
-
[[Category: Anomalous scattering]]
+
-
[[Category: Mannanase]]
+
[[Category: Trichoderma reesei]]
[[Category: Trichoderma reesei]]
-
 
+
[[Category: Murshudov G]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:32:40 2009''
+
[[Category: Penttila M]]
 +
[[Category: Sabini E]]
 +
[[Category: Schubert H]]
 +
[[Category: Siika-Aho M]]
 +
[[Category: Wilson KS]]

Current revision

The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5

PDB ID 1qns

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools