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1qq2

From Proteopedia

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{{Seed}}
 
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[[Image:1qq2.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23.==
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The line below this paragraph, containing "STRUCTURE_1qq2", creates the "Structure Box" on the page.
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<StructureSection load='1qq2' size='340' side='right'caption='[[1qq2]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qq2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QQ2 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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{{STRUCTURE_1qq2| PDB=1qq2 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qq2 OCA], [https://pdbe.org/1qq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qq2 RCSB], [https://www.ebi.ac.uk/pdbsum/1qq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qq2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRDX1_RAT PRDX1_RAT] Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qq/1qq2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qq2 ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23.===
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==See Also==
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*[[Peroxiredoxin|Peroxiredoxin]]
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*[[Peroxiredoxin 3D structures|Peroxiredoxin 3D structures]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_10535922}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 10535922 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_10535922}}
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==About this Structure==
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1QQ2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQ2 OCA].
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==Reference==
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<ref group="xtra">PMID:10535922</ref><references group="xtra"/>
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Abe, Y.]]
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[[Category: Abe Y]]
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[[Category: Hakoshima, T.]]
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[[Category: Hakoshima T]]
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[[Category: Hirotsu, S.]]
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[[Category: Hirotsu S]]
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[[Category: Hori, H.]]
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[[Category: Hori H]]
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[[Category: Nagahara, N.]]
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[[Category: Nagahara N]]
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[[Category: Nishino, T.]]
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[[Category: Nishino T]]
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[[Category: Okada, K.]]
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[[Category: Okada K]]
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[[Category: Oxidoreductase]]
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[[Category: Thioredoxin fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:10:41 2009''
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Current revision

CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23.

PDB ID 1qq2

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