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1qq9

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[[Image:1qq9.png|left|200px]]
 
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{{STRUCTURE_1qq9| PDB=1qq9 | SCENE= }}
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==STREPTOMYCES GRISEUS AMINOPEPTIDASE COMPLEXED WITH METHIONINE==
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<StructureSection load='1qq9' size='340' side='right'caption='[[1qq9]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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===STREPTOMYCES GRISEUS AMINOPEPTIDASE COMPLEXED WITH METHIONINE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1qq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QQ9 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10771423}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qq9 OCA], [https://pdbe.org/1qq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qq9 RCSB], [https://www.ebi.ac.uk/pdbsum/1qq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qq9 ProSAT]</span></td></tr>
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[[1qq9]] is a 1 chain structure of [[Aminopeptidase]] and [[Streptomyces griseus Aminopeptidase (SGAP)]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQ9 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/APX_STRGG APX_STRGG] An exopeptidase specific for larger hydrophobic amino acids (especially leucine), no cleavage occurs if the next residue is proline (PubMed:8444149).<ref>PMID:2503378</ref> <ref>PMID:8444149</ref> <ref>PMID:8665903</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qq/1qq9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qq9 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aminopeptidase|Aminopeptidase]]
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
*[[Streptomyces griseus Aminopeptidase (SGAP)|Streptomyces griseus Aminopeptidase (SGAP)]]
*[[Streptomyces griseus Aminopeptidase (SGAP)|Streptomyces griseus Aminopeptidase (SGAP)]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:010771423</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces griseus]]
[[Category: Streptomyces griseus]]
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[[Category: Blumberg, S.]]
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[[Category: Blumberg S]]
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[[Category: Gilboa, R.]]
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[[Category: Gilboa R]]
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[[Category: Greenblatt, H M.]]
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[[Category: Greenblatt HM]]
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[[Category: Lessel, U.]]
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[[Category: Lessel U]]
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[[Category: Perach, M.]]
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[[Category: Perach M]]
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[[Category: Schomburg, D.]]
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[[Category: Schomburg D]]
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[[Category: Shoham, G.]]
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[[Category: Shoham G]]
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[[Category: Spungin-Bialik, A.]]
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[[Category: Spungin-Bialik A]]
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[[Category: Calcium activation]]
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[[Category: Double-zinc metalloproteinaze]]
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[[Category: Hydrolase]]
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[[Category: Protein-inhibitor complex]]
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Current revision

STREPTOMYCES GRISEUS AMINOPEPTIDASE COMPLEXED WITH METHIONINE

PDB ID 1qq9

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