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1qy1

From Proteopedia

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[[Image:1qy1.png|left|200px]]
 
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{{STRUCTURE_1qy1| PDB=1qy1 | SCENE= }}
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==Thermodynamics of Binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the Major Urinary Protein==
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<StructureSection load='1qy1' size='340' side='right'caption='[[1qy1]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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===Thermodynamics of Binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the Major Urinary Protein===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1qy1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QY1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_14871097}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PRZ:2-ISOBUTYL-3-METHOXYPYRAZINE'>PRZ</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qy1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qy1 OCA], [https://pdbe.org/1qy1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qy1 RCSB], [https://www.ebi.ac.uk/pdbsum/1qy1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qy1 ProSAT]</span></td></tr>
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[[1qy1]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QY1 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MUP1_MOUSE MUP1_MOUSE] Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qy/1qy1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qy1 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Carbonic anhydrase|Carbonic anhydrase]]
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*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:014871097</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Bingham, R J.]]
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[[Category: Bingham RJ]]
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[[Category: Bodenhausen, G.]]
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[[Category: Bodenhausen G]]
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[[Category: Findlay, J B.C.]]
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[[Category: Findlay JBC]]
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[[Category: Homans, S W.]]
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[[Category: Homans SW]]
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[[Category: Hsieh, S Y.]]
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[[Category: Hsieh S-Y]]
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[[Category: Kalverda, A P.]]
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[[Category: Kalverda AP]]
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[[Category: Kjellberg, A.]]
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[[Category: Kjellberg A]]
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[[Category: Perazzolo, C.]]
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[[Category: Perazzolo C]]
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[[Category: Phillips, S E.V.]]
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[[Category: Phillips SEV]]
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[[Category: Seshadri, K.]]
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[[Category: Seshadri K]]
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[[Category: Trinh, C H.]]
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[[Category: Trinh CH]]
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[[Category: Turnbull, W B.]]
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[[Category: Turnbull WB]]
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[[Category: 2-methoxy-3-isobutylpyrazine]]
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[[Category: Beta-barrel]]
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[[Category: Lipocalin]]
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[[Category: Mup1]]
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[[Category: Transport protein]]
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Thermodynamics of Binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the Major Urinary Protein

PDB ID 1qy1

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