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1qyu

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{{Seed}}
 
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[[Image:1qyu.png|left|200px]]
 
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==Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluD==
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The line below this paragraph, containing "STRUCTURE_1qyu", creates the "Structure Box" on the page.
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<StructureSection load='1qyu' size='340' side='right'caption='[[1qyu]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1qyu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QYU FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1qyu| PDB=1qyu | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qyu OCA], [https://pdbe.org/1qyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qyu RCSB], [https://www.ebi.ac.uk/pdbsum/1qyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qyu ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RLUD_ECOLI RLUD_ECOLI] Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA. Isomerization occurs as a late step during the assembly of the large ribosomal subunit.<ref>PMID:11087118</ref> <ref>PMID:17937767</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qy/1qyu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qyu ConSurf].
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<div style="clear:both"></div>
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===Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluD===
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==See Also==
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*[[Guide-independent Pseudouridine synthase|Guide-independent Pseudouridine synthase]]
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*[[Pseudouridine synthase 3D structures|Pseudouridine synthase 3D structures]]
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== References ==
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The line below this paragraph, {{ABSTRACT_PUBMED_14730022}}, adds the Publication Abstract to the page
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 14730022 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_14730022}}
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==About this Structure==
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1QYU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QYU OCA].
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==Reference==
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Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli., Del Campo M, Ofengand J, Malhotra A, RNA. 2004 Feb;10(2):231-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14730022 14730022]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Pseudouridylate synthase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Del Campo M]]
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[[Category: Campo, M Del.]]
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[[Category: Malhotra A]]
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[[Category: Malhotra, A.]]
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[[Category: Ofengand J]]
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[[Category: Ofengand, J.]]
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[[Category: Catalytic domain]]
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[[Category: Pseudouridine synthase]]
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[[Category: Rlud]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 18:44:12 2008''
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Current revision

Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluD

PDB ID 1qyu

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