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Basigin
From Proteopedia
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== Function == | == Function == | ||
| - | '''Basigin''' or '''CD147''' or '''EMMORIN''' is a transmembranal glycoprotein which is a receptor for a variety of proteins<ref>PMID:26684586</ref>. | + | '''Basigin''' or '''CD147''' or '''EMMORIN''' is a transmembranal glycoprotein which is a receptor for a variety of proteins<ref>PMID:26684586</ref>. Basigin has several isoforms and contains immunoglobulin domains. |
== Disease == | == Disease == | ||
== Relevance == | == Relevance == | ||
| + | |||
| + | Basigin is involved in regulation of glycolysis and thus in development of malignant tumors and T-cell-mediated immunological disorders<ref>PMID:35844594</ref>. | ||
== Structural highlights == | == Structural highlights == | ||
Revision as of 09:51, 30 April 2024
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References
- ↑ Muramatsu T. Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners. J Biochem. 2016 May;159(5):481-90. PMID:26684586 doi:10.1093/jb/mvv127
- ↑ Xu Y, Chen Y, Zhang X, Ma J, Liu Y, Cui L, Wang F. Glycolysis in Innate Immune Cells Contributes to Autoimmunity. Front Immunol. 2022 Jul 1;13:920029. PMID:35844594 doi:10.3389/fimmu.2022.920029
