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8j73

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'''Unreleased structure'''
 
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The entry 8j73 is ON HOLD
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==Methylcrotonoyl-CoA carboxylase core-Dimer==
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<StructureSection load='8j73' size='340' side='right'caption='[[8j73]], [[Resolution|resolution]] 4.16&Aring;' scene=''>
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Authors: Liu, D.S., Su, J.Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8j73]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8J73 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8J73 FirstGlance]. <br>
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Description: Methylcrotonoyl-CoA carboxylase core-Dimer
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.16&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8j73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8j73 OCA], [https://pdbe.org/8j73 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8j73 RCSB], [https://www.ebi.ac.uk/pdbsum/8j73 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8j73 ProSAT]</span></td></tr>
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[[Category: Liu, D.S]]
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</table>
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[[Category: Su, J.Y]]
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== Disease ==
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[https://www.uniprot.org/uniprot/MCCB_HUMAN MCCB_HUMAN] 3-methylcrotonyl-CoA carboxylase deficiency. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/MCCB_HUMAN MCCB_HUMAN] Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.<ref>PMID:17360195</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Liu DS]]
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[[Category: Su JY]]

Current revision

Methylcrotonoyl-CoA carboxylase core-Dimer

PDB ID 8j73

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