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2kay

From Proteopedia

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[[Image:2kay.png|left|200px]]
 
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{{STRUCTURE_2kay| PDB=2kay | SCENE= }}
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==Solution structure and dynamics of S100A5 in the Ca2+ -bound states==
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<StructureSection load='2kay' size='340' side='right'caption='[[2kay]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2kay]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KAY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KAY FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kay FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kay OCA], [https://pdbe.org/2kay PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kay RCSB], [https://www.ebi.ac.uk/pdbsum/2kay PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kay ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S10A5_HUMAN S10A5_HUMAN] Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites.<ref>PMID:10882717</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/2kay_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kay ConSurf].
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<div style="clear:both"></div>
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===Solution structure and dynamics of S100A5 in the Ca2+ -bound states===
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==See Also==
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*[[S100 proteins 3D structures|S100 proteins 3D structures]]
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{{ABSTRACT_PUBMED_19536568}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2kay]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KAY OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:019536568</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bertini, I.]]
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[[Category: Large Structures]]
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[[Category: Gupta, S Das.]]
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[[Category: Bertini I]]
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[[Category: Hu, X.]]
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[[Category: Das Gupta S]]
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[[Category: Karavelas, T.]]
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[[Category: Hu X]]
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[[Category: Luchinat, C.]]
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[[Category: Karavelas T]]
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[[Category: Parigi, G.]]
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[[Category: Luchinat C]]
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[[Category: SPINE, Structural Proteomics in Europe.]]
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[[Category: Parigi G]]
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[[Category: Yuan, J.]]
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[[Category: Yuan J]]
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[[Category: Calcium binding protien]]
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[[Category: Ef-hand]]
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[[Category: Metal binding protein]]
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[[Category: S100a5]]
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[[Category: Spine]]
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[[Category: Spine2]]
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[[Category: Structural genomic]]
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[[Category: Structural proteomics in europe]]
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Current revision

Solution structure and dynamics of S100A5 in the Ca2+ -bound states

PDB ID 2kay

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