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2kqf

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==Solution structure of MAST205-PDZ complexed with the C-terminus of a rabies virus G protein==
==Solution structure of MAST205-PDZ complexed with the C-terminus of a rabies virus G protein==
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<StructureSection load='2kqf' size='340' side='right'caption='[[2kqf]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2kqf' size='340' side='right'caption='[[2kqf]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2kqf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KQF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2kqf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rabies_lyssavirus Rabies lyssavirus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KQF FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAST205 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kqf OCA], [https://pdbe.org/2kqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kqf RCSB], [https://www.ebi.ac.uk/pdbsum/2kqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kqf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kqf OCA], [https://pdbe.org/2kqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kqf RCSB], [https://www.ebi.ac.uk/pdbsum/2kqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kqf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MAST2_HUMAN MAST2_HUMAN]] Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).[UniProtKB:Q60592]
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[https://www.uniprot.org/uniprot/MAST2_HUMAN MAST2_HUMAN] Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).[UniProtKB:Q60592]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bernard, A]]
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[[Category: Rabies lyssavirus]]
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[[Category: Cordier, F]]
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[[Category: Bernard A]]
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[[Category: Delepierre, M]]
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[[Category: Cordier F]]
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[[Category: Lafon, M]]
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[[Category: Delepierre M]]
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[[Category: Simenel, C]]
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[[Category: Lafon M]]
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[[Category: Terrien, E]]
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[[Category: Simenel C]]
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[[Category: Wolff, N]]
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[[Category: Terrien E]]
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[[Category: Kinase]]
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[[Category: Wolff N]]
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[[Category: Mast205]]
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[[Category: Pdz complex and viral peptide]]
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[[Category: Pdz domain]]
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[[Category: Signaling protein-peptide binding protein complex]]
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Current revision

Solution structure of MAST205-PDZ complexed with the C-terminus of a rabies virus G protein

PDB ID 2kqf

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