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2lnh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2lnh is ON HOLD Authors: Aitio, O., Hellman, M., Skehan, B., Kesti, T., Leong, J.M., Saksela, K., Permi, P. Description: Enterohaemorrhagic E. coli...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Enterohaemorrhagic E. coli (EHEC) exploits a tryptophan switch to hijack host F-actin assembly== | |
| + | <StructureSection load='2lnh' size='340' side='right'caption='[[2lnh]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2lnh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LNH FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lnh OCA], [https://pdbe.org/2lnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lnh RCSB], [https://www.ebi.ac.uk/pdbsum/2lnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lnh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/WASL_HUMAN WASL_HUMAN] Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.<ref>PMID:19366662</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Wiskott-Aldrich syndrome protein 3D structures|Wiskott-Aldrich syndrome protein 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli O157:H7]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Aitio O]] | ||
| + | [[Category: Hellman M]] | ||
| + | [[Category: Kesti T]] | ||
| + | [[Category: Leong JM]] | ||
| + | [[Category: Permi P]] | ||
| + | [[Category: Saksela K]] | ||
| + | [[Category: Skehan B]] | ||
Current revision
Enterohaemorrhagic E. coli (EHEC) exploits a tryptophan switch to hijack host F-actin assembly
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