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2lp3
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2lp3 is ON HOLD Authors: Budzinska, M., Ruszczynska-Bartnik, K., Belczyk-Ciesielska, A., Bierzynski, A., Ejchart, A. Description: Solution structur...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of S100A1 Ca2+== | |
| + | <StructureSection load='2lp3' size='340' side='right'caption='[[2lp3]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2lp3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LP3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LP3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lp3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lp3 OCA], [https://pdbe.org/2lp3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lp3 RCSB], [https://www.ebi.ac.uk/pdbsum/2lp3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lp3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/S10A1_HUMAN S10A1_HUMAN] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. | ||
| - | + | ==See Also== | |
| - | + | *[[S100 proteins 3D structures|S100 proteins 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Belczyk-Ciesielska A]] | ||
| + | [[Category: Bierzynski A]] | ||
| + | [[Category: Budzinska M]] | ||
| + | [[Category: Ejchart A]] | ||
| + | [[Category: Ruszczynska-Bartnik K]] | ||
Current revision
Solution structure of S100A1 Ca2+
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