2m5h
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR structure note: solution structure of monomeric human FAM96A== | |
| - | + | <StructureSection load='2m5h' size='340' side='right'caption='[[2m5h]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2m5h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5H FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5h OCA], [https://pdbe.org/2m5h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m5h RCSB], [https://www.ebi.ac.uk/pdbsum/2m5h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CIA2A_HUMAN CIA2A_HUMAN] Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227).<ref>PMID:23891004</ref> <ref>PMID:25716227</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ouyang B]] | ||
| + | [[Category: Xia B]] | ||
Current revision
NMR structure note: solution structure of monomeric human FAM96A
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