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2m7b

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==ORF PP_3909 from Pseudomonas putida KT2440 encoding a protein similar to bacteriophage lambda ea8.5==
==ORF PP_3909 from Pseudomonas putida KT2440 encoding a protein similar to bacteriophage lambda ea8.5==
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<StructureSection load='2m7b' size='340' side='right' caption='[[2m7b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2m7b' size='340' side='right'caption='[[2m7b]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2m7b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psepk Psepk]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M7B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2m7b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida_KT2440 Pseudomonas putida KT2440]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M7B FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2m7a|2m7a]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PP_3909 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160488 PSEPK])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m7b OCA], [https://pdbe.org/2m7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m7b RCSB], [https://www.ebi.ac.uk/pdbsum/2m7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m7b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m7b OCA], [http://pdbe.org/2m7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m7b RCSB], [http://www.ebi.ac.uk/pdbsum/2m7b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2m7b ProSAT]</span></td></tr>
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</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q88G17_PSEPK Q88G17_PSEPK]
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A cluster of genes in the exoxis region of bacteriophage lambda are capable of inhibiting the initiation of DNA synthesis in Escherichia coli. The most indispensible gene in this region is ea8.5. Here, we report the nuclear magnetic resonance structures of two ea8.5 orthologs from enteropathogenic E. coli and Pseudomonas putida prophages. Both proteins are characterized by a fused homeodomain/zinc-finger fold that escaped detection by primary sequence search methods. While these folds are both associated with a nucleic acid binding function, the amino acid composition suggests otherwise, leading to the possibility that Ea8.5 associates with other viral and host proteins.
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The Solution Structures of Two Prophage Homologues of the Bacteriophage lambda Ea8.5 Protein Reveal a Newly Discovered Hybrid Homeodomain/Zinc-Finger Fold.,Kwan JJ, Smirnova E, Khazai S, Evanics F, Maxwell KL, Donaldson LW Biochemistry. 2013 May 14. PMID:23672713<ref>PMID:23672713</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 2m7b" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Psepk]]
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[[Category: Large Structures]]
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[[Category: Donaldson, L W.F]]
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[[Category: Pseudomonas putida KT2440]]
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[[Category: Bacteriophage]]
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[[Category: Donaldson LWF]]
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[[Category: Homeodomain]]
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[[Category: Putative transcription factor]]
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[[Category: Unknown function]]
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[[Category: Zinc binding]]
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Current revision

ORF PP_3909 from Pseudomonas putida KT2440 encoding a protein similar to bacteriophage lambda ea8.5

PDB ID 2m7b

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