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2vvm

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{{Seed}}
 
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[[Image:2vvm.png|left|200px]]
 
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==The structure of MAO-N-D5, a variant of monoamine oxidase from Aspergillus niger.==
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The line below this paragraph, containing "STRUCTURE_2vvm", creates the "Structure Box" on the page.
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<StructureSection load='2vvm' size='340' side='right'caption='[[2vvm]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2vvm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VVM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PRO:PROLINE'>PRO</scene></td></tr>
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{{STRUCTURE_2vvm| PDB=2vvm | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvm OCA], [https://pdbe.org/2vvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vvm RCSB], [https://www.ebi.ac.uk/pdbsum/2vvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vvm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AOFN_ASPNG AOFN_ASPNG]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vv/2vvm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vvm ConSurf].
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<div style="clear:both"></div>
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===THE STRUCTURE OF MAO-N-D5, A VARIANT OF MONOAMINE OXIDASE FROM ASPERGILLUS NIGER.===
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==See Also==
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*[[Monoamine oxidase|Monoamine oxidase]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 18951902 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18951902}}
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==About this Structure==
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2VVM is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVM OCA].
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==Reference==
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The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution., Atkin KE, Reiss R, Koehler V, Bailey KR, Hart S, Turkenburg JP, Turner NJ, Brzozowski AM, Grogan G, J Mol Biol. 2008 Dec 31;384(5):1218-31. Epub 2008 Oct 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18951902 18951902]
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[[Category: Aspergillus niger]]
[[Category: Aspergillus niger]]
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[[Category: Atkin, K E.]]
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[[Category: Large Structures]]
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[[Category: Brzozowski, A M.]]
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[[Category: Atkin KE]]
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[[Category: Grogan, G J.]]
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[[Category: Brzozowski AM]]
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[[Category: Hart, S.]]
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[[Category: Grogan GJ]]
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[[Category: Turkenburg, J P.]]
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[[Category: Hart S]]
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[[Category: Aspergillus niger]]
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[[Category: Turkenburg JP]]
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[[Category: Directed evolution variant]]
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[[Category: Enantioselectivity]]
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[[Category: Fad]]
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[[Category: Flavoprotein]]
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[[Category: Monoamine oxidase]]
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[[Category: Oxidoreductase]]
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[[Category: Peroxisome]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 17 13:02:22 2008''
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Current revision

The structure of MAO-N-D5, a variant of monoamine oxidase from Aspergillus niger.

PDB ID 2vvm

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