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2wab

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(New page: '''Unreleased structure''' The entry 2wab is ON HOLD Authors: Montainer, C., Money, V.A., Pires, V.M.R., Flint, J.E., Pinheiro, B.A., Goyal, A., Prates, J.A.M., Izumi, A., Stalbrand, H....)
Current revision (07:09, 1 May 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 2wab is ON HOLD
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==Structure of an active site mutant of a family two carbohydrate esterase from Clostridium thermocellum in complex with celluohexase==
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<StructureSection load='2wab' size='340' side='right'caption='[[2wab]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2wab]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WAB FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=PRD_900016:beta-cellopentaose'>PRD_900016</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wab OCA], [https://pdbe.org/2wab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wab RCSB], [https://www.ebi.ac.uk/pdbsum/2wab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wab ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CELE_ACET2 CELE_ACET2] Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan (PubMed:3066698, PubMed:1991028). Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) (PubMed:19338387).<ref>PMID:19338387</ref> <ref>PMID:1991028</ref> <ref>PMID:3066698</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/2wab_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wab ConSurf].
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<div style="clear:both"></div>
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Authors: Montainer, C., Money, V.A., Pires, V.M.R., Flint, J.E., Pinheiro, B.A., Goyal, A., Prates, J.A.M., Izumi, A., Stalbrand, H., Kolenova, K., Topakas, E., Dodson, E.J., Bolam, D.A., Davies, G.J., Fontes, C.M.G.A., Gilbert, H.J.
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==See Also==
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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Description: Structure of an active site mutant of a family two carbohydrate esterase from Clostridium thermocellum in complex with celluohexase
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== References ==
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<references/>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 25 09:18:50 2009''
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__TOC__
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</StructureSection>
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[[Category: Acetivibrio thermocellus]]
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[[Category: Large Structures]]
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[[Category: Bolam DN]]
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[[Category: Davies GJ]]
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[[Category: Dodson EJ]]
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[[Category: Flint JE]]
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[[Category: Fontes CMGA]]
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[[Category: Gilbert HJ]]
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[[Category: Goyal A]]
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[[Category: Izumi A]]
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[[Category: Kolenova K]]
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[[Category: Money VA]]
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[[Category: Montainer C]]
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[[Category: Pinheiro BA]]
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[[Category: Pires VMR]]
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[[Category: Prates JAM]]
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[[Category: Stalbrand H]]
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[[Category: Topakas E]]

Current revision

Structure of an active site mutant of a family two carbohydrate esterase from Clostridium thermocellum in complex with celluohexase

PDB ID 2wab

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