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2yhe
From Proteopedia
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| - | [[Image:2yhe.jpg|left|200px]] | ||
| - | < | + | ==Structure determination of the stereoselective inverting sec- alkylsulfatase Pisa1 from Pseudomonas sp.== |
| - | + | <StructureSection load='2yhe' size='340' side='right'caption='[[2yhe]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2yhe]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._DSM_6611 Pseudomonas sp. DSM 6611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YHE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YHE FirstGlance]. <br> | |
| - | or | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| - | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yhe OCA], [https://pdbe.org/2yhe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yhe RCSB], [https://www.ebi.ac.uk/pdbsum/2yhe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yhe ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RSAKS_PSESP RSAKS_PSESP] Alkylsulfatase that catalyzes the enantioselective hydrolysis of secondary-alkylsulfates with strict inversion of configuration, leading to the formation of homochiral (S)-configurated alcohols and nonreacted sulfate esters (PubMed:21770430, Ref.2, PubMed:23061549). The substrate spectrum includes a range of linear, branched or cyclic sec-alkylsulfates (PubMed:21770430). Can use sec-alkylsulfate esters bearing aromatic, olefinic and acetylenic moieties (Ref.2). Acts by cleaving the C-O bond, resulting in inversion at the carbon (PubMed:23061549).<ref>PMID:21770430</ref> <ref>PMID:23061549</ref> <ref>PMID:21770430</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Sulfatase 3D structures|Sulfatase 3D structures]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| - | [[Category: Pseudomonas sp. | + | </StructureSection> |
| - | [[Category: Faber | + | [[Category: Large Structures]] |
| - | [[Category: Kepplinger | + | [[Category: Pseudomonas sp. DSM 6611]] |
| - | [[Category: Knaus | + | [[Category: Faber K]] |
| - | [[Category: Macheroux | + | [[Category: Kepplinger B]] |
| - | [[Category: Schober | + | [[Category: Knaus T]] |
| - | [[Category: Wagner | + | [[Category: Macheroux P]] |
| - | + | [[Category: Schober M]] | |
| - | + | [[Category: Wagner UG]] | |
| - | + | ||
Current revision
Structure determination of the stereoselective inverting sec- alkylsulfatase Pisa1 from Pseudomonas sp.
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