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4bc2

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[[Image:4bc2.png|left|200px]]
 
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{{STRUCTURE_4bc2| PDB=4bc2 | SCENE= }}
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==Crystal structure of human D-xylulokinase in complex with D-xylulose and adenosine diphosphate==
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<StructureSection load='4bc2' size='340' side='right'caption='[[4bc2]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
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===Crystal structure of human D-xylulokinase in complex with D-xylulose and adenosine diphosphate===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4bc2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BC2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=XUL:D-XYLULOSE'>XUL</scene></td></tr>
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[[4bc2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BC2 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bc2 OCA], [https://pdbe.org/4bc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bc2 RCSB], [https://www.ebi.ac.uk/pdbsum/4bc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bc2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/XYLB_HUMAN XYLB_HUMAN] Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.<ref>PMID:23179721</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Xylulokinase]]
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[[Category: Large Structures]]
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[[Category: Baker, E N.]]
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[[Category: Baker EN]]
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[[Category: Bunker, R D.]]
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[[Category: Bunker RD]]
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[[Category: Loomes, K M.]]
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[[Category: Loomes KM]]
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[[Category: Fggy carbohydrate kinase]]
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[[Category: Glucuronate xylulokinase pathway]]
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[[Category: Transferase]]
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Current revision

Crystal structure of human D-xylulokinase in complex with D-xylulose and adenosine diphosphate

PDB ID 4bc2

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